- Код статьи
- 10.31857/S0040357124040054-1
- DOI
- 10.31857/S0040357124040054
- Тип публикации
- Статья
- Статус публикации
- Опубликовано
- Авторы
- Том/ Выпуск
- Том 58 / Номер выпуска 4
- Страницы
- 445-457
- Аннотация
- На фоне растущей потребности в устойчивых источниках энергии, конструкционных материалах и качественном продовольствии для увеличивающегося населения планеты все большее внимание исследователей сосредоточено на возможности биотрансформации газовых субстратов – источников углерода и энергии для уникальных микроорганизмов, использующих метан, моно- и диоксид углерода, водород в качестве питания. Помимо чистого научного интереса к изучению фундаментальных задач математического моделирования в биофизике и биохимии микроорганизмов, направление характеризуется высокой практической значимостью результатов исследований. В фокусе внимания исследователей несколько классов задач, включающих как использование возможностей генной инженерии по оптимизации метаболизма как эффективного способа получения широкого спектра продуктов, так и ключевые биокаталитические ферменты, а также разработку новых инженерных решений для биореакторов, подразумевающих повышение управляемости, безопасности и эффективности процесса биосинтеза, снижение затрат на получение продукта. Для изучения сравнительной эффективности существующих и перспективных биореакторов, прежде всего в части массообменных характеристик аппаратов и оптимизации показателей расхода энергии, сегодня доступен значительный спектр инструментов, включающий как методы математического описания двухфазной газожидкостной среды и гидродинамических процессов, так и возможности суперкомпьютерных вычислений, использование алгоритмов машинного обучения и нейросетей – в работе рассмотрен ряд примеров и современных тенденций по развитию направления газовой ферментации.
- Ключевые слова
- ферментация биореактор биоконверсия метана метанотрофы гидрогазодинамика математическое моделирование редактирование генома биотехнологии
- Дата публикации
- 07.08.2024
- Год выхода
- 2024
- Всего подписок
- 0
- Всего просмотров
- 41
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